| Abstrakt: |
Migratory insertion is a fundamental organometallic transformation that enables the functionalizationof an unsaturated bond. Recent reports on catalytic hydroamination provide evidencethat supports an intermolecular migratory insertion pathway featuring alkene insertion into metalnitrogen(M-N) bonds. This article presents factors influencing the rate of migratory insertion in latetransitionmetal-catalyzed hydroamination, including steric and electronic effects from ligands, alkenes,and metal centers, along with stabilization from coordinated amine intermediates and orderedtransition states. |
