| Autor: |
Goldstein, A, Fischli, W, Lowney, L I, Hunkapiller, M, Hood, L |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; November 1981, Vol. 78 Issue: 11 p7219-7223, 5p |
| Abstrakt: |
The full primary structure of the very potent opioid peptide dynorphin, from porcine pituitary, has been determined. It is (H)Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln(OH). The synthetic peptide with this sequence behaves identically to natural dynorphin in a number of ways, and it has the same potency in the guinea pig ileum myenteric plexus--longitudinal muscle bioassay. The potency is accounted for by the first 13 residues. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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