| Autor: |
Tonnelle, C, Cazenave, P A, Brézin, C, Fougereau, M |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; November 1981, Vol. 78 Issue: 11 p7088-7090, 3p |
| Abstrakt: |
Three anti-micrococcus antibodies of restricted heterogeneity have been isolated from the antisera of homozygous a100/a100 rabbits. Heavy chains contained an unusual methionine residue at position 87 that may correlate with the a100 specificity. From this position, the sequence of a stretch of 35-50 amino acid residues was determined, permitting the definition of variable (V), diversity(D), and joining (J) segments in rabbit Ig heavy chains, with their most probable boundaries. Rabbit D regions so defined appear to be highly variable, both in sequence and in length, which varies, in the heavy chains analyzed, between 6 and 11 residues. The J regions are highly homologous to the mouse J2 segment. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
