| Autor: |
Ren, Zhongxiang, Xu, Yetong, Li, Tiejun, Sun, Weizhong, Tang, Zhiru, Wang, Yongsheng, Zhou, Kaifeng, Li, Jigang, Ding, Qi, Liang, Kaiyang, Wu, Liuting, Yin, Yulong, Sun, Zhihong |
| Zdroj: |
Animal Nutrition; September 2022, Vol. 10 Issue: 1 p360-371, 12p |
| Abstrakt: |
Nicotinamide adenine dinucleotide (NAD+) is an enzyme cofactor, co-substrate, and redox factor in all living cells and is necessary for maintaining cell metabolism. It has been shown that appropriate supplementation of NAD+precursors or inhibition of NAD+-depleting enzymes can promote mitochondrial oxidative phosphorylation and improve host energy utilization efficiency. In addition, increasing evidence indicates that the gut microbiota plays a pivotal role in host metabolism. Theoretically, there should be a close correlation among NAD+, gut microbiota, and host metabolism; however, the information is limited. In this review, we summarize the metabolic process of NAD+and its impact on host metabolism, the link between gut microbiota and host metabolism, as well as the potential effects of NAD+on microbial metabolism, providing a new perspective on the interaction between gut microbiota and host metabolism. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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