Evaluation of Rapid Antigen Detection Kits for Detection of SARS-CoV-2 B.1.1.529

Autor: Mak, Gannon C. K., Lau, Stephen S. Y., Wong, Kitty K. Y., Lau, C. S., Lam, Edman T. K., Ng, Ken H. L., Chan, Rickjason C. W.
Zdroj: Dr. Sulaiman Al Habib Medical Journal; 20220101, Issue: Preprints p1-4, 4p
Abstrakt: Background: Currently, there is a lack of studies evaluating rapid antigen detection (RAD) kits to detect SARS-CoV-2 B.1.1.529. Objective: To evaluate the analytical sensitivity of seven RAD kits to detect SARS-CoV-2 B.1.1.529. Study design: The analytical sensitivity was determined by means of limit of detection (LOD). A dilution set using a respiratory specimen collected from a COVID-19 patient infected with SARS-CoV-2 B.1.1.529 was prepared. RT-PCR was used as a reference method. Results: The LOD results showed that all seven RAD kits had comparable analytical sensitivity for detection of SARS-CoV-2 B.1.1.529. Conclusions: The RAD kits selected in the current study may be used for first-line screening of the recently emerged SARS-CoV-2 B.1.1.529.
Databáze: Supplemental Index
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