Does uric acid-lowering treatment slow the progression of chronic kidney disease? A meta-analysis of randomised controlled trials

Autor: Bignardi, Paulo Roberto, Ido, Danielle Harumi, Garcia, Felipe Augusto Lopes, Braga, Lucas Mendes, Delfino, Vinicius Daher Alvares
Zdroj: Nefrología; 20220101, Issue: Preprints
Abstrakt: Introduction: Hyperuricemia has been proposed as an independent factor in the development and progression of chronic kidney disease (CKD). However, the effect of uric acid-lowering therapies on delaying CKD progression is still uncertain. Therefore, this systemic review aims to assess the effect of uric acid-lowering therapies on renal outcomes in pre-dialysis CKD patients.
Databáze: Supplemental Index