| Autor: |
Swierkosz, E M, Erdman, D D, Bonnot, T, Schneiderheinze, C, Waner, J L |
| Zdroj: |
Journal of Clinical Microbiology; July 1995, Vol. 33 Issue: 7 p1839-1841, 3p |
| Abstrakt: |
A parainfluenza 3 virus variant which failed to react with parainfluenza 3 virus-specific monoclonal anti-bodies from two commercial sources was isolated from a 14-month-old boy. Analysis of the coding region of the hemagglutinin-neuraminidase gene identified 36 nucleotide changes and 4 amino acid changes compared with a consensus sequence derived from strains isolated from 1957 through 1983. Two unique amino acid changes occurred at positions 174 and 283, which are close to identified epitopes in the hemagglutinin-neuraminidase protein. Ongoing viral surveillance to detect variants is important, particularly in regard to vaccine development. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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