Electron capture gas chromatography detection and mass spectrum identification of 3-(2'-ketohexyl)indoline in spinal fluids of patients with tuberculous meningitis

Autor: Brooks, J B, Choudhary, G, Craven, R B, Alley, C C, Liddle, J A, Edman, D C, Converse, J D
Zdroj: Journal of Clinical Microbiology; June 1977, Vol. 5 Issue: 6 p625-628, 4p
Abstrakt: A basic, extractable, indolic type of compound, which was derivatized with heptafluorobutyric anhydride and pyridine, was obtained from the cerebrospinal fluids of patients with acute tuberculous meningitis. The compound was detected by frequency-pulsed, modulated electron capture gas-liquid chromatography, and it was tentatively identified by mass spectrometry as 3-(2'-ketohexyl)indoline. The compound was found to be valuable for differentiating between tuberculous, cryptococcal, and aseptic meningitides.
Databáze: Supplemental Index