| Autor: |
Philippart, Anahí, Boccardi, Elena, Pontiroli, Lucia, Beltrán, Ana Maria, Inayat, Alexandra, Vitale-Brovarone, Chiara, Schwieger, Wilhelm, Spiecker, Erdmann, Boccaccini, Aldo Roberto |
| Zdroj: |
Advances in Science and Technology; October 2014, Vol. 96 Issue: 1 p54-60, 7p |
| Abstrakt: |
Novel silica-based bioactive glasses were successfully prepared by the sol-gel method. The optimized glass composition for fabrication of the scaffolds was (in mol.%) 60% SiO2 – 30% CaO - 5% Na2O - 5% P2O5 (60S30C5N5P). This composition was confirmed to develop a thick hydroxycarbonate apatite (HCA) layer in Simulated Body Fluid (SBF) after 7 days, as revealed by Fourier Transform Infrared Spectroscopy (FTIR), indicating the bioactive character of the scaffolds. The mesoporous nature of the glass structure allows the load of tetracycline and a sustained release of the drug in PBS during 7 days was measured. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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