Autor: |
Rhodes, J M, Bennedsen, J, Larsen, S O, Riisgaard, S, Spärck, J V |
Zdroj: |
Infection and Immunity; January 1979, Vol. 23 Issue: 1 p34-40, 7p |
Abstrakt: |
Mice undergoing graft-versus-host reaction, skin grafting, and inoculation with tumor cells were tested for nonspecific resistance by intravenous challenge with Listeria monocytogenes. Peritoneal exudate macrophages from mice treated in a similar manner were tested in vitro for increased degradation of [1-14C]glucose, ability to degrade antigen/antibody complexes, ability to inhibit intracellular growth of listeria, and staining for beta-galactosidase. There was good correlation between in vivo resistance towards L. monocytogenes and in vitro inhibition of intracellular growth. There was also good correlation between increase in beta-galactosidase and in vivo resistance in mice undergoing a graft-versus-host-reaction. |
Databáze: |
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