| Autor: |
Staton, G. J., Carter, S. D., Ainsworth, S., Mullin, J., Smith, R. F., Evans, N. J. |
| Zdroj: |
Infection and Immunity; February 2020, Vol. 88 Issue: 5 |
| Abstrakt: |
Bovine digital dermatitis (BDD), an infectious disease of the bovine foot with a predominant treponemal etiology, is a leading cause of lameness in dairy and beef herds worldwide. BDD is poorly responsive to antimicrobial therapy and exhibits a relapsing clinical course; an effective vaccine is therefore urgently sought. Using a reverse vaccinology approach, the present study surveyed the genomes of the three BDD-associated Treponemaphylogroups for putative ß-barrel outer membrane proteins and considered their potential as vaccine candidates. |
| Databáze: |
Supplemental Index |
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