| Autor: |
Li, Bowen, Luo, Bangke, Blakemore, Caroline A., Smith, Aaron C., Widlicka, Daniel W., Berritt, Simon, Tang, Wenjun |
| Zdroj: |
Organic Letters; 20210101, Issue: Preprints |
| Abstrakt: |
A practical and efficient synthesis of α-heteroaryl propionic esters is developed by employing palladium-catalyzed α-heteroarylation of silyl ketene acetals, forming a wide variety of α-heteroaryl propionic esters with various substituents and functionalities in high yields. The success of this transformation is credited to the development of the bulky P,P═O ligand. The method has provided an efficient synthesis of α-heteroaryl propionic acids. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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