| Autor: |
Muder, R R, Diven, W F, Yu, V L, Johnson, J |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; December 1982, Vol. 22 Issue: 6 p1076-1078, 3p |
| Abstrakt: |
A rapid, specific, and reproducible high-pressure liquid chromatographic method was developed for the determination of cefoperazone concentration in serum and tissue. The assay uses a simple methanol extraction, with cefoxitin as the internal standard. The limits of detection are 1 to 150 micrograms/ml; the maximum coefficient of variation is 7.4%. Using the same chromatography column, muBondapak phenyl, and mobile-phase 0.005 M tetrabutylammonium buffer-acetonitrile (80:20), the method can be easily adapted for the analysis of cefoxitin and moxalactam. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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