Genome-encoded cytoplasmic double-stranded RNAs, found in C9ORF72ALS-FTD brain, propagate neuronal loss

Autor: Rodriguez, Steven, Sahin, Asli, Schrank, Benjamin R., Al-Lawati, Hawra, Costantino, Isabel, Benz, Eric, Fard, Darian, Albers, Alefiya D., Cao, Luxiang, Gomez, Alexis C., Evans, Kyle, Ratti, Elena, Cudkowicz, Merit, Frosch, Matthew P., Talkowski, Michael, Sorger, Peter K., Hyman, Bradley T., Albers, Mark W.
Zdroj: Science Translational Medicine; July 2021, Vol. 13 Issue: 601 peaaz4699
Abstrakt: Genome-encoded cytoplasmic double-stranded RNAs elicit neuroinflammation and propagated neuronal death.
Databáze: Supplemental Index