Intermolecular Autolytic Cleavage Can Contribute to the Activation of Progelatinase A by Cell Membranes (∗)

Autor: Atkinson, Susan J., Crabbe, Thomas, Cowell, Susan, Ward, Robin V., Butler, Michael J., Sato, Hiroshi, Seiki, Motoharu, Reynolds, John J., Murphy, Gillian
Zdroj: Journal of Biological Chemistry; December 1995, Vol. 270 Issue: 51 p30479-30485, 7p
Abstrakt: Membrane-type matrix metalloproteinase (MT-MMP) messenger RNA and protein expression were shown to be elevated in human fibroblasts following treatment with concanavalin A, coincident with the induction of the ability to process progelatinase A.
Databáze: Supplemental Index