Autor: |
Lama, Raju, Binti Yusof, Wardah, Shrestha, Tilak R., Hanafi, Sarifah, Bhattarai, Matrika, Hassan, Rosline, Alwi Zilfalil, Bin |
Zdroj: |
Hematology/Oncology and Stem Cell Therapy; 20210101, Issue: Preprints |
Abstrakt: |
Beta-thalassemia is a genetic disorder that is inherited in an autosomal recessive pattern. This genetic disease leads to a defective beta-globin hemoglobin chain causing partial or complete beta-globin chain synthesis loss. Beta-thalassemia major patients need a continuous blood transfusion and iron chelation to maintain the normal homeostasis of red blood cells (RBCs) and other systems in the body. Patients also require treatment procedures that are costly and tedious, resulting in a serious health burden for developing nations such as Nepal. |
Databáze: |
Supplemental Index |
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