| Autor: |
Das, Shampa, Fitzgerald, Richard, Ullah, Asad, Bula, Marcin, Collins, Andrea M., Mitsi, Elena, Reine, Jesus, Hill, Helen, Rylance, Jamie, Ferreira, Daniela M., Tripp, Karen, Bertasini, Andrea, Franzoni, Samantha, Massimiliano, Mameli, Lahlou, Omar, Motta, Paola, Barth, Philip, Velicitat, Patrick, Knechtle, Philipp, Hope, William |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; October 2020, Vol. 65 Issue: 1 |
| Abstrakt: |
Cefepime-enmetazobactam is a novel β-lactam–β-lactamase inhibitor combination with broad-spectrum antimicrobial activity against a range of multidrug-resistant Enterobacteriaceae. This agent is being developed for a range of serious hospital infections. An understanding of the extent of partitioning of β-lactam–β-lactamase inhibitor combinations into the human lung is required to better understand the potential role of cefepime-enmetazobactam for the treatment of nosocomial pneumonia. |
| Databáze: |
Supplemental Index |
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