Haemodialysis-induced pulmonary granulocyte sequestration in rabbits is organ specific.

Autor: van Teijlingen, Marco E, Nubé, Menso J, ter Wee, Piet M, van Wijhe, Michiel H, Borgdorff, Piet, Tangelder, Geert-Jan
Zdroj: Nephrology Dialysis Transplantation; December 2003, Vol. 18 Issue: 12 p2589-2595, 7p
Abstrakt: Haemodialysis (HD) with cuprophan (CU) dialysers leads to a severe transient granulocytopenia. In the present study, we challenge the hypothesis that granulocytes sequester within the pulmonary vasculature simply because this is the first vascular bed encountered. This hypothesis is based upon experiments in which activated plasma or complement fragments were infused into animals, and may not pertain to the more complex HD situation.
Databáze: Supplemental Index