| Autor: |
Shaw, C. D., Imamura, H., Downing, T., Blackburn, G., Westrop, G. D., Cotton, J. A., Berriman, M., Sanders, M., Rijal, S., Coombs, G. H., Dujardin, J. C., Carter, K. C. |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; September 2019, Vol. 64 Issue: 1 |
| Abstrakt: |
Understanding the mechanism(s) underpinning drug resistance could lead to novel treatments to reverse the increased tolerance of a pathogen. In this study, paromomycin (PMM) resistance (PMMr) was induced in three Nepalese clinical strains of Leishmania donovaniwith different inherent susceptibilities to antimony (Sb) drugs by stepwise exposure of promastigotes to PMM. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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