THE SPECIFICITY OF 4-AMINOPTEROYLGLUTAMIC ACID (AMINOPTERIN) FOR LEUKEMIC HEMATOPOIETIC TISSUE

Autor: SKIPPER, HOWARD E., RISER, WILLIAM H., NOLAN, CONSTANCE W.
Zdroj: Blood; April 1950, Vol. 5 Issue: 4 p358-371, 14p
Abstrakt: A study of the effect of aminopterin on the hematopoietic tissue of normal mice and mice with transplanted Ak 4 leukemia is reported. At less than lethal doses, aminopterin showed a striking inhibition specificity for neoplastic cell production.
Databáze: Supplemental Index