| Autor: |
Rao, N, Whitsett, CF, Oxendine, SM, Telen, MJ |
| Zdroj: |
Blood; February 1993, Vol. 81 Issue: 3 p815-819, 5p |
| Abstrakt: |
The Cartwright (Yt) blood group antigens have previously been shown likely to reside on a phosphatidylinositol-linked erythrocyte membrane protein. In this study, an unusual individual whose red blood cells (RBCs) were of the previously unreported Yt(a-b-) phenotype were used, along with normal Yt(a+) cells, to investigate serologically and biochemically the relationship of the Yta antigen to known phosphatidylinositol-linked erythrocyte proteins. Yt(a-b-) RBCs expressed normal amounts of various phosphatidyl-inositol-linked proteins except acetylcholinesterase. Further, human anti-Yta reacted with acetylcholinesterase in immunoprecipitation and immunoblotting studies. Thus, acetylcholinesterase is now identified as the protein bearing the Yt blood group antigens. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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