| Autor: |
Nocchi, Samara Requena, Kato, Natália Naomi, de Almeida, Julio Menta, Ferreira, Alda Maria Teixeira, Toffoli-Kadri, Mônica Cristina, de Freitas Meirelles, Lyvia Eloiza, Damke, Gabrielle Marconi Zago Ferreira, Consolaro, Marcia Edilaine Lopes, Rigo, Graziela Vargas, Macedo, Alexandre José, Tasca, Tiana, dos Reis, Sharon Vieira, Alves, Flavio Macedo, Carollo, Carlos Alexandre, Silva, Denise Brentan |
| Zdroj: |
Revista Brasileira de Farmacognosia; 20240101, Issue: Preprints p1-5, 5p |
| Abstrakt: |
Iridoids are secondary metabolites with several biological activities. They are often found in species of the genus TabebuiaGomes ex A.P. de Candolle. Tabebuia aurea(Silva Manso) Benth. & Hook. F. ex S. Moore, Bignoniaceae, is used to treat snake bites in traditional medicine. This study aimed to isolate the specioside - an the iridoid glycoside - from T. aurea, as well as investigate its potential biological properties, including anti-inflammatory, antibacterial, antibiofilm, cytotoxic, anti-Trichomonas vaginalisand antitrypanosomal activities. Specioside inhibited leucocyte recruitment into the peritoneal cavity in mice injected with carrageenan, data that demonstrated its anti-inflammatory potential. However, the additional evaluated biological properties were negligible. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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