Alzheimer's Prevention Initiative Generation Program: Development of an APOEgenetic counseling and disclosure process in the context of clinical trials

Autor: Langlois, Carolyn M., Bradbury, Angela, Wood, Elisabeth M., Roberts, J. Scott, Kim, Scott Y.H., Riviere, Marie-Emmanuelle, Liu, Fonda, Reiman, Eric M., Tariot, Pierre N., Karlawish, Jason, Langbaum, Jessica B.
Zdroj: Alzheimer's & Dementia: Translational Research & Clinical Interventions; January 2019, Vol. 5 Issue: 1 p705-716, 12p
Abstrakt: As the number of Alzheimer's disease (AD) prevention studies grows, many individuals will need to learn their genetic and/or biomarker risk for the disease to determine trial eligibility. An alternative to traditional models of genetic counseling and disclosure is needed to provide comprehensive standardized counseling and disclosure of apolipoprotein E (APOE) results efficiently, safely, and effectively in the context of AD prevention trials.
Databáze: Supplemental Index