Cyclosporine A as a potential neuroprotective agent: a study of prolonged hypothermic circulatory arrest in a chronic porcine model.

Autor: Hagl, C, Tatton, N A, Weisz, D J, Zhang, N, Spielvogel, D, Shiang, H H, Bodian, C A, Griepp, R B
Zdroj: European Journal of Cardio-Thoracic Surgery; June 2001, Vol. 19 Issue: 6 p756-764, 9p
Abstrakt: To assess whether Cyclosporine A (CsA) or cycloheximide (CHX) can reduce ischemia-induced neurological damage by blocking apoptotic pathways, we assessed their effects on cerebral recovery in a chronic animal model of hypothermic circulatory arrest (HCA).
Databáze: Supplemental Index