Schistosoma haematobiuminfection in western Madagascar: morbidity determined by ultrasonography

Autor: Serieye, J., Boisier, P., Ravaoalimalala, V.E., Ramarokoto, C.E., Leutscher, P., Esterre, P., Roux, J.
Zdroj: Transactions of the Royal Society of Tropical Medicine & Hygiene; August 1996, Vol. 90 Issue: 4 p398-401, 4p
Abstrakt: To assess the morbidity related to Schistosoma haematobiuminfection in western Madagascar, an ultrasonographic examination was performed of 574 inhabitants >5 years old in a village in an old-established endemic area where no prior systematic antischistosomal treatment had been given. The overall prevalence of infection was 75.9% and the geometric mean egg count of positive individuals was 36 eggs/10 mL of urine Recent haematuria had been experienced by 31.8% of individuals. Echographic abnormalities of the urinary tract were present in 50.5% of individuals: they were more frequent in males. Bladder wall lesions were observed in 93.1% of individuals with ultrasonographic changes, irregularities of the inner surface being the most comon finding. Congestive changes were noted in 8.4% of kidneys, but we observed only 4 severe congestions. Bladder lesions and congestive changes in kidneys predominated in youth; their presence and severity were significantly correlated with egg excretion. In 12 inhabitants, grade 1 periportal fibrosis was observed, but no significant association was found with S. haematobiuminfection. In a control village, where the prevalence of S. haematobiuminfection was 7%, moderate congestion of kidneys was observed in 2% of examined inhabitants, and bladder changes in 6%, with a significant relationship with S. haematobiuminfection.
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