Phenolic Constituents from Xyloselinum leonidii

Autor: Hanh, Nguyen Phuong, Khang, Nguyen Sinh, Ha, Chu Thi Thu, Binh, Nguyen Quoc, Dat, Nguyen Tien
Zdroj: Natural Product Communications; November 2018, Vol. 13 Issue: 11
Abstrakt: One new and seven known phenolic compounds were isolated from the twigs of Xyloselinum leonidii, and identified by means of spectroscopic methods. They were identified to be a new hydroxyaetophenone, xyloselin (1) together with four coumarins decursinol (2), decursinol glucoside (3), pteryxin (4), and praeroside I (5), two chromones angelicain (6), and cimifugin (7), and a flavonoid hesperidin (8). Among the isolated compounds, pteryxin showed the strongest inhibitory effect on the nitric oxide production (IC50= 17.4 μM) while xyloselin showed weak inhibition. The present paper is the first report on the phenolic contents and the anti-inflammatory activity of the genus Xyloselinum.
Databáze: Supplemental Index