| Autor: |
Lafreniere, Jean Francois, Mills, Philippe, Tremblay, Jacques Pierre, Fahime, Elmostafa El |
| Zdroj: |
Transplantation; June 2004, Vol. 77 Issue: 11 p1741-1747, 7p |
| Abstrakt: |
A main technological problem related to the clinical application of myoblast transplantation is the poor migration of transplanted cells. In this study, we investigated a new physiologic approach that consists of coinjecting motogenic factors insulin growth factor (IGF)-1 or basic fibroblast growth factor (bFGF) to enhance the migration of human skeletal myoblasts. Among the different ways by which those factors can induce the cell migration processes, we investigated their capacity to enhance cell endogenous proteolytic activity that will help transplanted cells to migrate through the extracellular matrix. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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