| Autor: |
RAO, PATRICIA E., OLINI, GILBERT, KILLE, JOHN, MUCHMORE, ELIZABETH, TALLE, MARY ANNE, BRAKE, GARRY, RUDNICK, SETH A. |
| Zdroj: |
Transplantation; October 1991, Vol. 52 Issue: 4 p691-697, 7p |
| Abstrakt: |
Chimpanzees were injected with OKT3 and two other anti-CD3 antibodies, OKT3D and OKT3E. Both of the new antibodies were of the mouse IgG2b isotype. Administration of the antibodies was identical to the clinical regimen used for OKT3 in humans: 5 mg i.v., daily for 10 consecutive days. All animals were monitored for fever during administration of the antibodies, and blood samples were taken throughout the treatment period for monitoring the effects of the antibodies on peripheral lymphocyte subsets and the appearance of circulating cytokines. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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