| Autor: |
Raynal, Isabelle, Prigent, Philippe, Peyramaure, Sophie, Najid, Abderrahim, Rebuzzi, Cécile, Corot, Claire |
| Zdroj: |
Investigative Radiology; January 2004, Vol. 39 Issue: 1 p56-63, 8p |
| Abstrakt: |
Superparamagnetic iron oxides (SPIO) used as magnetic resonance (MR) contrast agents undergo specific uptake by macrophages. The purpose of this study was first to determine the mechanism of macrophage uptake for Ferumoxides by using competition experiments with specific ligands of scavenger receptors SR-A (I/II) and second, to evaluate and compare the internalization of 2 different contrast agents, Ferumoxides (SPIO) and Ferumoxtran-10 (USPIO: ultrasmall superparamagnetic iron oxide) using macrophages obtained by chemical activation of human monocytic cells. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
