Cerebrospinal fluid and Serum creatine kinase BB activity after outofhospital cardiac arrest

Autor: Longstreth, W. T., Clayson, Kathleen J., Sumi, S. Mark
Zdroj: Neurology (Ovid); April 1981, Vol. 31 Issue: 4 p455-458, 4p
Abstrakt: In patients resuscitated from out-of-hospital cardiac arrest, neurologic outcome was compared with creatine kinase isoen-zyme BB activity (CKBB) in cerebrospinal fluid (CSF) in 20 patients and in serum in 52 patients. CSF CKBB was 2 units Der liter or less in patients with complete neurologic recovery but was significantly elevated in patients without neurologic recovery (mean, 55 units per liter) or with incomplete neurologic recovery (mean, 7 units per liter). Serum CKBB was detected more than 6 hours after cardiac arrest in only 4 of patients with complete neurologic recovery but in all patients without neurologic recovery. These results demonstrate a relationship between CSF and serum CKBB and neurologic outcome after cardiac arrest.
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