| Autor: |
Cairncross, J. Gregory, Macdonald, David R., Pexman, J. H. Warwick, Ives, F. Jay |
| Zdroj: |
Neurology (Ovid); May 1988, Vol. 38 Issue: 5 p724-726, 3p |
| Abstrakt: |
The magnitude and time course of steroid-induced CT changes were analyzed in 11 patients with recurrent malignant glioma. CTs were obtained before and at regular intervals after starting dexamethasone (16 mg/d). Midline shift, ventricular compression, edema, enhancement intensity, and the size of the enhancing mass often improved with steroid treatment. Improvement occurred within 2 weeks in most instances. Changes in the volume of the enhancing tumor were assessed quantitatively in eight patients. In six, the mass was smaller after 2 weeks of steroid therapy, and in two the reduction approached 50. Steroid-induced CT changes can mimic treatment responses. If steroids are necessary for symptom control, patients should be taking these medications for 2 weeks before a baseline CT is obtained and investigational treatment started. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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