Autor: |
Wang, Yibo, Chen, Jinxing, Zhang, Yu, Yu, Weifeng, Zhang, Channa, Gong, Ling, Shao, Liying, Lu, Jinguo, Gao, Yang, Chen, Xuannan, Chen, Xi, Hui, Rutai |
Zdroj: |
Circulation: Cardiovascular Genetics; June 2013, Vol. 6 Issue: 3 p271-278, 8p |
Abstrakt: |
Two endophenotypes of arterial calcification, calcification on arterial wall and calcification in atherosclerotic plaques, are associated with different types of cardiovascular events. Mgp-deficient mice showed matrix Gla protein (MGP) is strongly associated with calcification on arterial wall without atherosclerotic plaques, and MGPvariants were not significantly associated with myocardial infarction. MGP may play different roles in the 2 endophenotypes. |
Databáze: |
Supplemental Index |
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