Autor: |
Sulimovici, Sorel, Roginsky, Martin S. |
Zdroj: |
European Journal of Endocrinology; March 1980, Vol. 93 Issue: 3 p346-350, 5p |
Abstrakt: |
The effect of streptozotocin-induced diabetes on the in vitro conversion of vitamin D3to 25-hydroxyvitamin D3(25-OHD3) by isolated liver microsomes from rachitic rats was examined. Enzymic activity was significantly less than that observed in control animals (P< 0.001). Administration of insulin restored activity almost to control values. These findings provide evidence that diabetes in this animal model produces alterations in the metabolism of vitamin D. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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