| Autor: |
Eldering, Joyce A., Kocher, Markus, Clemetson, Jeannine M., Clemetson, Kenneth J., Frey, Felix J., Frey, Brigitte M. |
| Zdroj: |
FEBS Letters; March 1993, Vol. 318 Issue: 3 p231-234, 4p |
| Abstrakt: |
The present investigation revealed the presence of lipocortins I and IV, but not lipocortins II and VI, in human platelets. Lipocortin I was found in the Triton‐soluble fraction of both resting and thrombin‐activated platelets and was not covalently bound to skeletal components. Without detergents, when resting platelets were lysed and fractionated in the absence of Ca2+, lipocortin I was found only in the cytosolic fraction, whereas, in the presence of Ca2+, lipocortin I was associated only with the crude particulate and not with the membrane nor the cytosolic fractions. |
| Databáze: |
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| Externí odkaz: |
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