Development and Regulation of Dendritic Spine Synapses

Autor: Calabrese, Barbara, Wilson, Margaret S., Halpain, Shelley
Zdroj: Physiology; February 2006, Vol. 21 Issue: 1 p38-47, 10p
Abstrakt: Dendritic spines are small protrusions from neuronal dendrites that form the postsynaptic component of most excitatory synapses in the brain. They play critical roles in synaptic transmission and plasticity. Recent advances in imaging and molecular technologies reveal that spines are complex, dynamic structures that contain a dense array of cytoskeletal, transmembrane, and scaffolding molecules. Several neurological and psychiatric disorders exhibit dendritic spine abnormalities.
Databáze: Supplemental Index