| Autor: |
Furth, Paul S., Reitman, Michael S., Gentles, Robert, Cook, Alan F. |
| Zdroj: |
Tetrahedron Letters; January 1997, Vol. 38 Issue: 38 p6643-6646, 4p |
| Abstrakt: |
Three amino-ether derivatives have been prepared by a solid-phase synthesis using a novel amidine-based linker. The sequence of reactions involved a) amine exchange of a solid-supported dimethylformamidine with a secondary amine, b) α-alkylation of the solid-supported formamidine with an aromatic aldehyde, c) alkylation of the newly generated hydroxyl group with a benzylic halide, and d) cleavage of the formamidine linkage to the solid support. © 1997 Elsevier Science Ltd. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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