PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λproduction

Autor: Werder, Rhiannon B., Lynch, Jason P., Simpson, Jennifer C., Zhang, Vivian, Hodge, Nick H., Poh, Matthew, Forbes-Blom, Elizabeth, Kulis, Christina, Smythe, Mark L., Upham, John W., Spann, Kirsten, Everard, Mark L., Phipps, Simon
Zdroj: Science Translational Medicine; May 2018, Vol. 10 Issue: 440
Abstrakt: RSV-induced prostaglandin D2 release contributes to disease severity by impairing IFN-λ production.
Databáze: Supplemental Index