| Autor: |
Greco, Claudia, Corsi, Anna, Caputo, Marco, Cavallari, Andrea, Calabresi, Federico |
| Zdroj: |
Tumori Journal; April 1979, Vol. 65 Issue: 2 p169-180, 12p |
| Abstrakt: |
In the present report, investigations have been carried out to evaluate toxic and therapeutic effects of cyclophosphamide vs its isomer iphosphamide. Cytostatic action of the 2 drugs was assayed on the murine Lewis lung carcinoma (3LL). It has been observed that iphosphamide is less toxic as compared to cyclophosphamide (LD50IPLD50CP=1.5); on the other hand, to reach the same therapeutic effectiveness on 3LL, an iphosphamide dose 1.6 - 2 times higher than that of its parent compound is necessary. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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