Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling
Autor: | Dobbins, Jessica, Gagnon, Etienne, Godec, Jernej, Pyrdol, Jason, Vignali, Dario A. A., Sharpe, Arlene H., Wucherpfennig, Kai W. |
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Zdroj: | Science Signaling; July 2016, Vol. 9 Issue: 438 pra75-ra75, 1p |
Abstrakt: | Ligand binding to the T cell costimulatory receptor CD28 releases its cytoplasmic domain from the plasma membrane to initiate signaling. |
Databáze: | Supplemental Index |
Externí odkaz: |