Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling

Autor: Dobbins, Jessica, Gagnon, Etienne, Godec, Jernej, Pyrdol, Jason, Vignali, Dario A. A., Sharpe, Arlene H., Wucherpfennig, Kai W.
Zdroj: Science Signaling; July 2016, Vol. 9 Issue: 438 pra75-ra75, 1p
Abstrakt: Ligand binding to the T cell costimulatory receptor CD28 releases its cytoplasmic domain from the plasma membrane to initiate signaling.
Databáze: Supplemental Index