puckered, a gene involved in position-specific cell differentiation in the dorsal epidermis of the Drosophilalarva

Autor: Ring, J. M., Martinez Arias, A.
Zdroj: Development; December 1993, Vol. 119 Issue: 4 p251-259, 9p
Abstrakt: The final pattern of the cuticle of the Drosophilalarva depends on the position-specific behaviour of the epidermal cells during their differentiation. This behaviour is dictated, in part, by the relative position of the cells during embryogenesis which allows them to receive and integrate signals from their neighbours. The translation of this ‘positional information’ into pattern might depend on the activity of genes that are able to integrate the outcome of cell interactions and tranfer it to the genes responsible for cell differentiation. Mutations in the gene puckeredcause spatially restricted defects during the differentiation of the larval epidermal cells. We present data that suggests puckeredmay be involved in linking positional information to cell differentiation.
Databáze: Supplemental Index