| Autor: |
Toure, P., Villena, F., Melikyan, G. G. |
| Zdroj: |
Organic Letters; November 2002, Vol. 4 Issue: 23 p3989-3992, 4p |
| Abstrakt: |
The relative stabilities of thymidine-3,5-diphosphoric acid (1) derived isomeric cations and radicals were calculated and key geometric parameters were thoroughly analyzed. The most probable sites of a hydride-ion (1, 2, 5-Me) and H-atom (4, 5, 5-Me) abstraction were identified, thus allowing prediction of the regioselectivity of potential damage to the deoxyribose ring and thymine moiety caused by carcinogenic agents of electrophilic and radical nature. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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