| Autor: |
Doll, Katharina, Fadeeva, Elena, Stumpp, Nico S., Grade, Sebastian, Chichkov, Boris N., Stiesch, Meike |
| Zdroj: |
BioNanoMaterials; May 2016, Vol. 17 Issue: 1-2 p53-57, 5p |
| Abstrakt: |
Implant-associated infections still pose serious problems in modern medicine. The development of fabrication processes to generate functional surfaces, which inhibit bacterial attachment, is of major importance. Sharklet™-like as well as grooves and grid micro-structures having similar dimensions were fabricated on the common implant material titanium by ultra-short pulsed laser ablation. Investigations on the biofilm formation of Staphylococcus aureusfor up to 24 h revealed similarly reduced bacterial surface coverage on all micro-structures investigated compared to smooth titanium surfaces. This study is a prove-of-principle and could serve as basis for further investigations towards a structure-based biofilm-inhibiting implant. |
| Databáze: |
Supplemental Index |
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