Is the frequency of mitoses and PCNA positive cells in tissues affected by delay in fixation? Lessons for accurate tumor grading

Autor: Laroye, Guy J.
Zdroj: Pathology; January 1996, Vol. 28 Issue: 4 p328-333, 6p
Abstrakt: Using uniform systematic random sampling, we tested whether a drop in mitoses and PCNA (proliferation celt nuclear antigen) positive cells following a delay in tissue fixation of up to five hours, would be unequivocally discernible at the well perfused periphery from 11 aggressive rat adenocarcinomas. No statistically significant difference (0.05
Databáze: Supplemental Index