Spectrophotometric Titration of Sulfonamides with Bromate-Bromide Solution

Autor: Agarwal, Suraj P., Walash, Mohammed I., Blake, Martin I.
Zdroj: Journal of Pharmaceutical Sciences; May 1972, Vol. 61 Issue: 5 p779-781, 3p
Abstrakt: A spectrophotometric titration procedure for the analysis of sulfanilic acid and a number of sulfonamide drugs is described. The drug dissolved in a mixture of concentrated hydrochloric acid and glacial acetic acid (2:8) is titrated with a 0.1 Nbromate-bromide mixture. The end-point is determined spectrophotometrically at 345nm. Quantitative recoveries are reported for 10 sulfonamides. Good agreement between the proposed and the official procedure is obtained.
Databáze: Supplemental Index