| Autor: |
de Oliveira, Raimundo Gonçalves, Souza, Grasielly Rocha, Guimarães, Amanda Leite, de Oliveira, Ana Paula, Silva Morais, Amanda Caroline, da Cruz Araújo, Edigênia Cavalcante, Nunes, Xirley Pereira, Almeida, Jackson Roberto Guedes da Silva |
| Zdroj: |
Journal of Young Pharmacists; September 2013, Vol. 5 Issue: 3 p102-105, 4p |
| Abstrakt: |
The antioxidant and photoprotective activities of dried extracts from the leaves of Encholirium spectabilewere investigated. It was also evaluated the total phenolic and flavonoid contents by the Folin–Ciocalteu and aluminum chloride methods, respectively. Antioxidant activities of the extracts were evaluated by using of 2,2-diphenyl-1-picrylhydrazil (DPPH) radical scavenging and β-carotene–linoleic acid bleaching and compared with ascorbic acid, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) used as reference compounds. The photoprotective effect was evaluated by the spectrophotometric method. The most significant total phenolic and flavonoid contents was of 188.50 ± 27.50 mg of gallic acid equivalent/g and 129.70 ± 4.59 mg of catechin equivalent/g, respectively, for chloroform fraction (Es-CHCl3). The Es-CHCl3also presented the best antioxidant activity (IC5025.35 ± 4.35 μg/ml) for DPPH scavenging. The ethanol extract (Es-EtOH), Es-CHCl3and the fraction ethyl acetate (Es-AcOEt) showed characteristic absorption bands in regions UVB and UVA in a concentration-dependent manner. Es-CHCl3presented the highest sun protection factor SPF (8.89 ± 2.11). It shows the possibility to use this extract as sunscreen in pharmaceutical preparations. |
| Databáze: |
Supplemental Index |
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