Hormonal Regulation of Complement Factor B in Human Endometrium

Autor: HASTY, LISA A., BROCKMAN, WENDY W., LAMBRIS, JOHN D., LYTTLE, C. RICHARD
Zdroj: American Journal of Reproductive Immunology; September 1993, Vol. 30 Issue: 3 p63-67, 5p
Abstrakt: PROBLEM: Recent investigations have demonstrated the presence of complement components in human endometrium in a cycle‐specific manner. Luteal phase endometrium has been shown to synthesize complement C3 de novo, whereas proliferative endometrium produces little or no C3. Likewise factor B. which is critical to the activation of the alternative pathway of complement, has been shown to be present only in the glandular epithelium of luteal phase endometrium. This investigation was designed to determine if factor B is present in the endometrium in a high progesterone state such as pregnancy or with exogenous progesterone treatment.
Databáze: Supplemental Index