| Autor: |
Rokita, E, Mutsaers, P.H.A, Quaedackers, J.A, Tatoń, G, de Voigt, M.J.A |
| Zdroj: |
Nuclear Instruments and Methods in Physics Research Section B; September 1999, Vol. 158 Issue: 1-4 p412-417, 6p |
| Abstrakt: |
The proton microprobe in combination with proton induced X-ray emission (micro-PIXE) and with proton induced gamma-ray emission (micro-PIGE) are used to determine quantitatively the modulation of inorganic deposits formation by Sr and F ions in a cell culture model. The results indicate that the process may be investigated by the micro-PIXE determination of the amount of calcium deposited. It was found that F-treatment stimulate bone formation at doses much lower than Sr. At high doses an impaired mineralization is found for both elements. It was found that the mechanisms responsible for of F and Sr incorporations are different. The minimal F and Sr concentrations in the medium at which the incorporation may be investigated by micro-PIGE and micro-PIXE amount to ∼0.02 mg/l and <0.08 mg/l, respectively. |
| Databáze: |
Supplemental Index |
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