| Autor: |
Madsen, Arthur J., Peter, Edward T., Nicoloff, Demetre M., Walder, Arnold I., Wangensteen, Owen H. |
| Zdroj: |
JAMA: Journal of the American Medical Association; February 1963, Vol. 183 Issue: 7 p541-542, 2p |
| Abstrakt: |
HISTAMINE has long been recognized as a vasoactive agent. Schayer1 has recently presented data supporting the concept that histamine regulates the microcirculation under normal physiologic conditions independent of other nervous or humeral influences. Histamine appears to play a role in several pathologic conditions among them endotoxin and analphalactic shock as well as allergies of various kinds. The histamine gastric secretory test has been a fundamental, clinical, and research tool. While investigating the gastric blood flow response to histamine infusion,2 the mesenteric artery blood flow was also determined and this forms the basis for this report.MethodMongrel dogs weighing from 10 to 12 kg (22 to 26.4 lb) were anesthetized with intravenous pentobarbitol. Blood pressure was monitored through a polyethylene catheter placed in the femoral artery connected to a stathum P23-AA strain gauge. Mesenteric artery flow was measured with a noncannulating gated electromagnetic flowmeter. Portal |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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