| Abstrakt: |
Although a large number of therapeutic measures have been utilized through the years in attempts to control the lesions of disseminated blastomycosis, it is only recently that these efforts have been attended with success. The introduction of a group of compounds, the diamidines, into clinical use, has ushered in a new era in the control of deep mycotic infections.* Two cases of widespread blastomycosis have been treated with stilbamidine † (4,4′-stilbenedicarboxamidine) by me and are described below:Case 1.—A 38-year-old white man, employed as a rose grower. The first sign of illness was the appearance of two small, infiltrated, erythematous, 0.5 cm. by 0.8 cm. nodes on the left arm about Aug. 15, 1951. Shortly afterward, the patient was prostrated because of the onset of chills, fever, polyarthralgia, and bronchitis. He was hospitalized elsewhere, and biopsy specimens were obtained from the two nodes. In the meantime, his blood was found |
