| Autor: |
Demetriou, Achilles A., Franco, Israel, Bark, Staffan, Rettura, Giuseppe, Seifter, Eli, Levenson, Stanley M. |
| Zdroj: |
Archives of Surgery; February 1984, Vol. 119 Issue: 2 p161-165, 5p |
| Abstrakt: |
• Vitamin A may play a role systemically and locally in controlling intra-abdominal sepsis. Adult male rats were divided into three groups. Group 1 ate a standard rat laboratory chow (not vitamin A deficient), group 2 ate the same chow supplemented with vitamin A, and group 3 ate the chow supplemented with beta carotene. All animals underwent cecal ligation, and the cecum was perforated either with a 27-gauge or an 18-gauge needle. Vitamin A dietary supplementation had a significant protective effect, which was manifested by improved survival in the animals whose cecum was perforated with an 18-gauge needle, prevention of postoperative hypothermia, maintenance of peripheral WBC counts at normal or above-normal values, and better localization of the intra-abdominal inflammatory process. Dietary supplementation with beta carotene had a lesser protective effect.(Arch Surg 1984;119:161-165) |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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